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AM-251 and SR144528 are acyl CoA:cholesterol acyltransferase inhibitors
Oxysterol-induced macrophage apoptosis may have a role in atherosclerosis. Macrophages lacking the type 2 cannabinoid receptor (CB2) are partially resistant to apoptosis induced by 7-ketocholesterol (7KC). AM-251 and SR144528 are selective antagonists of CB1 and CB2 receptors, respectively. We obser...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665256/ https://ncbi.nlm.nih.gov/pubmed/19338772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.02.020 |
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