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Rimonabant is a dual inhibitor of acyl CoA:cholesterol acyltransferases 1 and 2
Acyl-coenzymeA:cholesterol acyltransferase (ACAT) catalyzes the intracellular synthesis of cholesteryl esters (CE). Both ACAT isoforms, ACAT1 and ACAT2, play key roles in the pathophysiology of atherosclerosis and ACAT inhibition retards atherosclerosis in animal models. Rimonabant, a type 1 cannabi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918681/ https://ncbi.nlm.nih.gov/pubmed/20609360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.06.134 |
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