AM-251 and SR144528 are acyl CoA:cholesterol acyltransferase inhibitors

Oxysterol-induced macrophage apoptosis may have a role in atherosclerosis. Macrophages lacking the type 2 cannabinoid receptor (CB2) are partially resistant to apoptosis induced by 7-ketocholesterol (7KC). AM-251 and SR144528 are selective antagonists of CB1 and CB2 receptors, respectively. We obser...

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Bibliographic Details
Main Authors:	Thewke, Douglas, Freeman-Anderson, Natalie, Pickle, Theresa, Netherland, Courtney, Chilton, Courtney
Format:	Artigo
Language:	Inglês
Published:	2009
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2665256/ https://ncbi.nlm.nih.gov/pubmed/19338772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.02.020
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AM-251 and SR144528 are acyl CoA:cholesterol acyltransferase inhibitors

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