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Acyl-coenzyme A: cholesterol acyltransferase promotes oxidized LDL/oxysterol-induced apoptosis in macrophages

7-Ketocholesterol (7KC) is a cytotoxic component of oxidized low density lipoproteins (OxLDLs) and induces apoptosis in macrophages by a mechanism involving the activation of cytosolic phospholipase A(2) (cPLA(2)). In the current study, we examined the role of ACAT in 7KC-induced and OxLDL-induced a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Freeman, Natalie E., Rusinol, Antonio E., Linton, MacRae, Hachey, David L., Fazio, Sergio, Sinensky, Michael S., Thewke, Douglas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768430/
https://ncbi.nlm.nih.gov/pubmed/15995174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M500101-JLR200
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