A Hydrogen Bond in Loop A Is Critical for the Binding and Function of the 5-HT(3) Receptor

Lignende værker

• 5-Fluorotryptamine is a partial agonist at 5-HT(3) receptors, and reveals that size and electronegativity at the 5 position of tryptamine are critical for efficient receptor function
  af: Bower, Kiowa S., et al.
  Udgivet: (2008)
• Probing the Role of Backbone Hydrogen Bonding in a Critical β-sheet of the Extracellular Domain of a Cys-loop Receptor
  af: Gleitsman, Kristin R., et al.
  Udgivet: (2009)
• A Coupled Array of Noncovalent Interactions Impacts the Function of the 5-HT(3)A Serotonin Receptor in an Agonist-Specific Way
  af: Miles, Timothy F., et al.
  Udgivet: (2012)
• Tyrosine Residues That Control Binding and Gating in the 5-Hydroxytryptamine(3) Receptor Revealed by Unnatural Amino Acid Mutagenesis
  af: Beene, Darren L., et al.
  Udgivet: (2004)
• Defining the roles of Asn-128, Glu-129 and Phe-130 in loop A of the 5-HT(3) receptor
  af: SULLIVAN, NORA L., et al.
  Udgivet: (2006)