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Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

Notch and Wnt signals play essential roles in intestinal development and homeostasis, yet how they integrate their action to affect intestinal morphogenesis is not understood. We examined the interplay between these two signaling pathways in vivo, by modulating Notch activity in mice carrying either...

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Main Authors: Fre, Silvia, Pallavi, S. K., Huyghe, Mathilde, Laé, Marick, Janssen, Klaus-Peter, Robine, Sylvie, Artavanis-Tsakonas, Spyros, Louvard, Daniel
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649205/
https://ncbi.nlm.nih.gov/pubmed/19251639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900427106
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