Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

Notch and Wnt signals play essential roles in intestinal development and homeostasis, yet how they integrate their action to affect intestinal morphogenesis is not understood. We examined the interplay between these two signaling pathways in vivo, by modulating Notch activity in mice carrying either...

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Bibliographic Details
Main Authors: Fre, Silvia, Pallavi, S. K., Huyghe, Mathilde, Laé, Marick, Janssen, Klaus-Peter, Robine, Sylvie, Artavanis-Tsakonas, Spyros, Louvard, Daniel
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649205/
https://ncbi.nlm.nih.gov/pubmed/19251639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900427106
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