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Putative Re-entrant Loop 1 of AE2 Transmembrane Domain Has a Major Role in Acute Regulation of Anion Exchange by pH
Normal pH sensitivity of the SLC4A2/AE2 anion exchanger requires transmembrane domain (TMD) amino acid (aa) residues not conserved in the homologous but relatively pH-insensitive SLC4A1/AE1 polypeptide. We tested the hypothesis that the nonconserved aa cluster (1075)DKPK(1078) within the first putat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2649077/ https://ncbi.nlm.nih.gov/pubmed/19103596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802051200 |
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