Acute regulation of mouse AE2 anion exchanger requires isoform-specific amino acid residues from most of the transmembrane domain

The widely expressed anion exchanger polypeptide AE2/SLC4A2 is acutely inhibited by acidic intracellular (pH(i)), by acidic extracellular pH (pH(o)), and by the calmodulin inhibitor, calmidazolium, whereas it is acutely activated by NH(4)(+). The homologous erythroid/kidney AE1/SLC4A1 polypeptide is...

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Detalhes bibliográficos
Main Authors: Stewart, A K, Kurschat, C E, Vaughan-Jones, R D, Shmukler, B E, Alper, S L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2007
Assuntos:
Cellular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277056/
https://ncbi.nlm.nih.gov/pubmed/17690150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.136119
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