Computationally Driven, Quantitative Experiments Discover Genes Required for Mitochondrial Biogenesis

Mitochondria are central to many cellular processes including respiration, ion homeostasis, and apoptosis. Using computational predictions combined with traditional quantitative experiments, we have identified 100 proteins whose deficiency alters mitochondrial biogenesis and inheritance in Saccharom...

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Hauptverfasser: Hess, David C., Myers, Chad L., Huttenhower, Curtis, Hibbs, Matthew A., Hayes, Alicia P., Paw, Jadine, Clore, John J., Mendoza, Rosa M., Luis, Bryan San, Nislow, Corey, Giaever, Guri, Costanzo, Michael, Troyanskaya, Olga G., Caudy, Amy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648979/
https://ncbi.nlm.nih.gov/pubmed/19300474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000407
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