Computationally Driven, Quantitative Experiments Discover Genes Required for Mitochondrial Biogenesis

Mitochondria are central to many cellular processes including respiration, ion homeostasis, and apoptosis. Using computational predictions combined with traditional quantitative experiments, we have identified 100 proteins whose deficiency alters mitochondrial biogenesis and inheritance in Saccharom...

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Detalhes bibliográficos
Main Authors: Hess, David C., Myers, Chad L., Huttenhower, Curtis, Hibbs, Matthew A., Hayes, Alicia P., Paw, Jadine, Clore, John J., Mendoza, Rosa M., Luis, Bryan San, Nislow, Corey, Giaever, Guri, Costanzo, Michael, Troyanskaya, Olga G., Caudy, Amy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648979/
https://ncbi.nlm.nih.gov/pubmed/19300474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000407
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