The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast

Since complete redundancy between extant duplicates (paralogs) is evolutionarily unfavorable, some degree of functional congruency is eventually lost. However, in budding yeast, experimental evidence collected for duplicated metabolic enzymes and in global physical interaction surveys had suggested...

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Detalhes bibliográficos
Main Authors: Musso, Gabriel, Costanzo, Michael, Huangfu, ManQin, Smith, Andrew M., Paw, Jadine, San Luis, Bryan-Joseph, Boone, Charles, Giaever, Guri, Nislow, Corey, Emili, Andrew, Zhang, Zhaolei
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493398/
https://ncbi.nlm.nih.gov/pubmed/18463300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.076174.108
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