Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

Th17 cells are involved in the pathogenesis of many autoimmune diseases, but it is not clear whether they play a pathogenic role in type 1 diabetes. Here we investigated whether mouse Th17 cells with specificity for an islet antigen can induce diabetes upon transfer into NOD/SCID recipient mice. Ind...

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Autori principali: Bending, David, De La Peña, Hugo, Veldhoen, Marc, Phillips, Jenny M., Uyttenhove, Catherine, Stockinger, Brigitta, Cooke, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648686/
https://ncbi.nlm.nih.gov/pubmed/19188681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37865
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