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An early age-related increase in the frequency of CD4(+) Foxp3(+) cells in BDC2·5NOD mice

The role of regulatory T cells (Treg) in maintaining tolerance to self has been intensively scrutinized, particularly since the discovery of Foxp3 as a Treg-specific transcription factor. The BDC2·5NOD transgenic mouse is an excellent model of immunoregulation because it has a very low incidence of...

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Detalhes bibliográficos
Main Authors: Thomas, David C, Mellanby, Richard J, Phillips, Jenny M, Cooke, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265971/
https://ncbi.nlm.nih.gov/pubmed/17437531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02604.x
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