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An early age-related increase in the frequency of CD4(+) Foxp3(+) cells in BDC2·5NOD mice
The role of regulatory T cells (Treg) in maintaining tolerance to self has been intensively scrutinized, particularly since the discovery of Foxp3 as a Treg-specific transcription factor. The BDC2·5NOD transgenic mouse is an excellent model of immunoregulation because it has a very low incidence of...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265971/ https://ncbi.nlm.nih.gov/pubmed/17437531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02604.x |
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