MT1-MMP and RECK are involved in human CD34(+) progenitor cell retention, egress, and mobilization

The mechanisms governing hematopoietic progenitor cell mobilization are not fully understood. We report higher membrane type 1–MMP (MT1-MMP) and lower expression of the MT1-MMP inhibitor, reversion-inducing cysteine-rich protein with Kazal motifs (RECK), on isolated circulating human CD34(+) progeni...

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主要な著者: Vagima, Yaron, Avigdor, Abraham, Goichberg, Polina, Shivtiel, Shoham, Tesio, Melania, Kalinkovich, Alexander, Golan, Karin, Dar, Ayelet, Kollet, Orit, Petit, Isabelle, Perl, Orly, Rosenthal, Ester, Resnick, Igor, Hardan, Izhar, Gellman, Yechiel N., Naor, David, Nagler, Arnon, Lapidot, Tsvee
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2009
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648678/
https://ncbi.nlm.nih.gov/pubmed/19197139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36541
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