Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcγRIIa and the integrin β3 cytoplasmic domain

Thrombocytopenia and thrombosis following treatment with the integrin αIIbβ3 antagonist eptifibatide are rare complications caused by patient antibodies specific for ligand-occupied αIIbβ3. Whether such antibodies induce platelet clearance by simple opsonization, by inducing mild platelet activation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gao, Cunji, Boylan, Brian, Bougie, Dan, Gill, Joan C., Birenbaum, Jessica, Newman, Debra K., Aster, Richard H., Newman, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648674/
https://ncbi.nlm.nih.gov/pubmed/19197137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36745
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados