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INTERACTIONS BETWEEN HSP70 AND THE HYDROPHOBIC CORE OF ALPHA–SYNUCLEIN INHIBIT FIBRIL ASSEMBLY
Molecular chaperones of the heat shock protein 70 (Hsp70) family counteract protein misfolding in a variety of neurodegenerative disease models. To determine whether human Hsp70 exerts similar effects on the aggregation of alpha-synuclein (α-Syn), the key component of insoluble fibrils present in Pa...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2008
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2648307/ https://ncbi.nlm.nih.gov/pubmed/18975920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801475r |
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