Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes

Several studies have demonstrated that intrastriatal injections of fibrillar α-synuclein in rodent brain induced a Parkinson’s disease-like propagation of Lewy body pathology with significant nigrostriatal neurodegeneration. This study evaluated the pathological features when exogenous α-synuclein p...

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Vydáno v:Brain
Hlavní autoři: Chu, Yaping, Muller, Scott, Tavares, Adriana, Barret, Olivier, Alagille, David, Seibyl, John, Tamagnan, Gilles, Marek, Ken, Luk, Kelvin C, Trojanowski, John Q, Lee, Virginia M Y, Kordower, Jeffrey H
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962904/
https://ncbi.nlm.nih.gov/pubmed/31580415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awz296
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