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Role of Insulin and Growth Hormone/Insulin-Like Growth Factor-I Signaling in Lifespan Extension: Rodent Longevity Models for Studying Aging and Calorie Restriction

Insulin/insulin-like growth factor-I (IGF-I) pathways are recognized as critical signaling pathways involved in the control of lifespans in lower organisms to mammals. Caloric restriction (CR) reduces plasma concentration of insulin, growth hormone (GH), and IGF-I. CR retards various age-dependent d...

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Sonraí Bibleagrafaíochta
Main Authors: Chiba, T, Yamaza, H, Shimokawa, I
Formáid: Artigo
Teanga:Inglês
Foilsithe: Bentham Science Publishers Ltd. 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647154/
https://ncbi.nlm.nih.gov/pubmed/19412415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920207783591726
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