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Growth hormone signaling is necessary for lifespan extension by dietary methionine
Growth hormone significantly impacts lifespan in mammals. Mouse longevity is extended when growth hormone (GH) signaling is interrupted but markedly shortened with high-plasma hormone levels. Methionine metabolism is enhanced in growth hormone deficiency, for example, in the Ames dwarf, but suppress...
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Publicado no: | Aging Cell |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BlackWell Publishing Ltd
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244257/ https://ncbi.nlm.nih.gov/pubmed/25234161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12269 |
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