Growth hormone signaling is necessary for lifespan extension by dietary methionine

Growth hormone significantly impacts lifespan in mammals. Mouse longevity is extended when growth hormone (GH) signaling is interrupted but markedly shortened with high-plasma hormone levels. Methionine metabolism is enhanced in growth hormone deficiency, for example, in the Ames dwarf, but suppress...

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Bibliografski detalji
Izdano u:Aging Cell
Glavni autori: Brown-Borg, Holly M, Rakoczy, Sharlene G, Wonderlich, Joseph A, Rojanathammanee, Lalida, Kopchick, John J, Armstrong, Vanessa, Raasakka, Debbie
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2014
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244257/
https://ncbi.nlm.nih.gov/pubmed/25234161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12269
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