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Growth hormone signaling is necessary for lifespan extension by dietary methionine
Growth hormone significantly impacts lifespan in mammals. Mouse longevity is extended when growth hormone (GH) signaling is interrupted but markedly shortened with high-plasma hormone levels. Methionine metabolism is enhanced in growth hormone deficiency, for example, in the Ames dwarf, but suppress...
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| Publicado en: | Aging Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244257/ https://ncbi.nlm.nih.gov/pubmed/25234161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12269 |
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