Divergent roles of sphingosine kinases in kidney ischemia-reperfusion injury

Sphingosine-1-phosphate (S1P), produced by sphingosine kinase 1 (SphK1) or kinase 2 (SphK2), mediates biological effects through intracellular and/or extracellular mechanisms. Here we determined a role for these kinases in kidney injury of wild-type mice following ischemia-reperfusion. SphK1 but not...

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Hlavní autoři: Jo, Sang-Kyung, Bajwa, Amandeep, Ye, Hong, Vergis, Amy L., Awad, Alaa S., Kharel, Yugesh, Lynch, Kevin R., Okusa, Mark D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646633/
https://ncbi.nlm.nih.gov/pubmed/18971925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2008.400
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