Glycogen synthase kinase 3β missplicing contributes to leukemia stem cell generation

Recent evidence suggests that a rare population of self-renewing cancer stem cells (CSC) is responsible for cancer progression and therapeutic resistance. Chronic myeloid leukemia (CML) represents an important paradigm for understanding the genetic and epigenetic events involved in CSC production. C...

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Bibliographic Details
Main Authors: Abrahamsson, Annelie E., Geron, Ifat, Gotlib, Jason, Dao, Kim-Hien T., Barroga, Charlene F., Newton, Isabel G., Giles, Francis J., Durocher, Jeffrey, Creusot, Remi S., Karimi, Mobin, Jones, Carol, Zehnder, James L., Keating, Armand, Negrin, Robert S., Weissman, Irving L., Jamieson, Catriona H. M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646624/
https://ncbi.nlm.nih.gov/pubmed/19237556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900189106
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