Glycogen synthase kinase 3β missplicing contributes to leukemia stem cell generation

Recent evidence suggests that a rare population of self-renewing cancer stem cells (CSC) is responsible for cancer progression and therapeutic resistance. Chronic myeloid leukemia (CML) represents an important paradigm for understanding the genetic and epigenetic events involved in CSC production. C...

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Detalhes bibliográficos
Main Authors: Abrahamsson, Annelie E., Geron, Ifat, Gotlib, Jason, Dao, Kim-Hien T., Barroga, Charlene F., Newton, Isabel G., Giles, Francis J., Durocher, Jeffrey, Creusot, Remi S., Karimi, Mobin, Jones, Carol, Zehnder, James L., Keating, Armand, Negrin, Robert S., Weissman, Irving L., Jamieson, Catriona H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646624/
https://ncbi.nlm.nih.gov/pubmed/19237556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900189106
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