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Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activity
Cells have evolved a signaling pathway called the spindle assembly checkpoint (SAC) to increase the fidelity of chromosome segregation by generating a “wait anaphase” signal until all chromosomes are properly aligned within the mitotic spindle. It has been proposed that tension generated by the stre...
Gespeichert in:
| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646557/ https://ncbi.nlm.nih.gov/pubmed/19193623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200808130 |
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