Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family

Individual members of the retinoblastoma (Rb) tumor suppressor gene family serve critical roles in the control of cellular proliferation and differentiation but the extent of their contributions is masked by redundant and compensatory mechanisms. Here, we employed a conditional knockout strategy to...

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Hlavní autoři: Viatour, Patrick, Somervaille, Tim C., Venkatasubrahmanyam, Shivkumar, Kogan, Scott, McLaughlin, Margaret E., Weissman, Irving L., Butte, Atul J., Passegué, Emmanuelle, Sage, Julien
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646421/
https://ncbi.nlm.nih.gov/pubmed/18940733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.07.009
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