Effects of TNFα-Converting Enzyme Inhibition on Amyloid β Production and APP Processing In Vitro and In Vivo

Tumor necrosis factor-α (TNFα) is a proinflammatory cytokine that is elevated in Alzheimer's disease (AD) brains. Because TNFα is released from cell membranes by the TNFα-converting enzyme (TACE), inhibition of TACE has the potential to mitigate TNFα effects in AD brain. TACE also cleaves amylo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kim, Minkyu L., Zhang, Bin, Mills, Ian P., Milla, Marcos E., Brunden, Kurt R., Lee, Virginia M.-Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646261/
https://ncbi.nlm.nih.gov/pubmed/19005070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2913-08.2008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados