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The influence of tumour necrosis factor- α (TNF-α) on amyloid-β (Aβ)-degrading enzymes in vitro

Pro-inflammatory cytokines, such as tumour necrosis factor-α (TNF-α), are increased in serum and CSF in Alzheimer's disease (AD). We investigated the effect of TNF-α on gene and protein expression levels of Aβ degrading enzymes (ACE, ECE-1, ECE- 2, IDE and NEP) in vitro. Differentiated (DC) and...

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Bibliografische gegevens
Hoofdauteurs: Culpan, Doris, Palmer, Jennifer, Miners, J Scott, Love, Seth, Kehoe, Patrick G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243456/
https://ncbi.nlm.nih.gov/pubmed/22200003
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