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Neprilysin Protects against Cerebral Amyloid Angiopathy and Aβ‐Induced Degeneration of Cerebrovascular Smooth Muscle Cells
Neprilysin (NEP), which degrades amyloid‐β (Aβ), is expressed by neurons and cerebrovascular smooth muscle cells (CVSMCs). NEP immunolabeling is reduced within cerebral blood vessels of Alzheimer's disease (AD) patients with cerebral amyloid angiopathy (CAA). We have now measured NEP enzyme act...
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| Publié dans: | Brain Pathol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Publishing Ltd
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8094282/ https://ncbi.nlm.nih.gov/pubmed/21382117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00486.x |
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