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Changes in Water Structure Induced by the Guanidinium Cation and Implications for Protein Denaturation

The effect of the guanidinium cation on the hydrogen bonding strength of water was analyzed using temperature-excursion Fourier transform infrared spectra of the OH stretching vibration in 5% H(2)O / 95% D(2)O solutions containing a range of different guanidine-HCl and guanidine-HBr concentrations....

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Main Authors: Scott, J. Nathan, Nucci, Nathaniel V., Vanderkooi, Jane M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646201/
https://ncbi.nlm.nih.gov/pubmed/18839935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp8058239
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