Urea and Guanidinium Chloride Denature Protein L in Different Ways in Molecular Dynamics Simulations

In performing protein-denaturation experiments, it is common to employ different kinds of denaturants interchangeably. We make use of molecular dynamics simulations of Protein L in water, in urea, and in guanidinium chloride (GdmCl) to ascertain if there are any structural differences in the associa...

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Bibliografiske detaljer
Main Authors: Camilloni, C., Rocco, A. Guerini, Eberini, I., Gianazza, E., Broglia, R. A., Tiana, G.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2008
Fag:
Biophysical Theory and Modeling
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397339/
https://ncbi.nlm.nih.gov/pubmed/18339753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.125799
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