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Urea and Guanidinium Chloride Denature Protein L in Different Ways in Molecular Dynamics Simulations
In performing protein-denaturation experiments, it is common to employ different kinds of denaturants interchangeably. We make use of molecular dynamics simulations of Protein L in water, in urea, and in guanidinium chloride (GdmCl) to ascertain if there are any structural differences in the associa...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2397339/ https://ncbi.nlm.nih.gov/pubmed/18339753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.125799 |
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