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Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7
Raf kinase inhibitory protein (RKIP) negatively regulates the MAP kinase (MAPK), G protein-coupled receptor kinase-2, and NF-κB signalling cascades. RKIP has been implicated as a metastasis suppressor for prostate cancer, but the mechanism is not known. Here, we show that RKIP inhibits invasion by m...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646152/ https://ncbi.nlm.nih.gov/pubmed/19153603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.294 |
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