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Mitochondrial abnormalities in spinal and bulbar muscular atrophy
Spinal and bulbar muscular atrophy (SBMA) is a motor neuron disease caused by polyglutamine expansion mutation in the androgen receptor (AR). We investigated whether the mutant protein alters mitochondrial function. We found that constitutive and doxycycline-induced expression of the mutant AR in MN...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2644643/ https://ncbi.nlm.nih.gov/pubmed/18824496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn310 |
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