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PKCδ survival signaling in cells containing an activated p21(Ras) protein requires PDK1

Protein kinase C δ (PKC δ) modulates cell survival and apoptosis in diverse cellular systems. We recently reported that PKCδ functions as a critical anti-apoptotic signal transducer in cells containing activated p21(Ras) and results in the activation of AKT, thereby promoting cell survival. How PKCδ...

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Detalhes bibliográficos
Main Authors: Xia, Shuhua, Chen, Zhihong, Forman, Lora W., Faller, Douglas V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644428/
https://ncbi.nlm.nih.gov/pubmed/19146951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.12.002
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