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PKCδ is Required for Survival of Cells Expressing Activated p21(Ras)

Inhibition of PKC activity in transformed cells and tumor cells containing activated p21(Ras) results in apoptosis. To investigate the pro-apoptotic pathway induced by the p21(Ras) oncoprotein, we first identified the specific PKC isozyme necessary to prevent apoptosis in the presence of activated p...

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Detalhes bibliográficos
Main Authors: Xia, Shuhua, Forman, Lora W., Faller, Douglas V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527128/
https://ncbi.nlm.nih.gov/pubmed/17350960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M610225200
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