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Delineation of Alternative Conformational States in E.coli Peptide Deformylase via Thermodynamic Studies for the Binding of Actinonin

We investigated the binding of a naturally occurring antibiotic, actinonin, to the Ni(2+) reconstituted recombinant form of E. coli peptide deformylase (PDF(Ec)) via isothermal titration microcalorimetry. The binding data conformed to both exothermic and endothermic phases with magnitudes of ΔG°, ΔH...

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Bibliografski detalji
Glavni autori: Berg, Alexander K., Srivastava, D. K.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644421/
https://ncbi.nlm.nih.gov/pubmed/19191548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8019542
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