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Expression of the Reverse Tetracycline-Transactivator Gene Causes Emphysema-Like Changes in Mice

The doxycycline-inducible, gene regulatory system allows tight control of transgene expression for the study of organ development and disease pathogenesis. Multiple recent reports have employed this model to investigate various lung diseases including emphysema. For our study, we used this transgeni...

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Detalhes bibliográficos
Main Authors: Sisson, Thomas H., Hansen, Jean M., Shah, Mitali, Hanson, Kerstin E., Du, Ming, Ling, Tony, Simon, Richard H., Christensen, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644220/
https://ncbi.nlm.nih.gov/pubmed/16415250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0378OC
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