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Expression of the Reverse Tetracycline-Transactivator Gene Causes Emphysema-Like Changes in Mice

The doxycycline-inducible, gene regulatory system allows tight control of transgene expression for the study of organ development and disease pathogenesis. Multiple recent reports have employed this model to investigate various lung diseases including emphysema. For our study, we used this transgeni...

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Bibliografiske detaljer
Main Authors: Sisson, Thomas H., Hansen, Jean M., Shah, Mitali, Hanson, Kerstin E., Du, Ming, Ling, Tony, Simon, Richard H., Christensen, Paul J.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644220/
https://ncbi.nlm.nih.gov/pubmed/16415250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0378OC
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