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Expression of the Reverse Tetracycline-Transactivator Gene Causes Emphysema-Like Changes in Mice

The doxycycline-inducible, gene regulatory system allows tight control of transgene expression for the study of organ development and disease pathogenesis. Multiple recent reports have employed this model to investigate various lung diseases including emphysema. For our study, we used this transgeni...

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Autori principali: Sisson, Thomas H., Hansen, Jean M., Shah, Mitali, Hanson, Kerstin E., Du, Ming, Ling, Tony, Simon, Richard H., Christensen, Paul J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644220/
https://ncbi.nlm.nih.gov/pubmed/16415250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0378OC
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