Lentiviral vectors encoding tetracycline-dependent repressors and transactivators for reversible knockdown of gene expression: a comparative study

BACKGROUND: RNA interference (RNAi)-mediated by the expression of short hairpin RNAs (shRNAs) has emerged as a powerful experimental tool for reverse genetic studies in mammalian cells. A number of recent reports have described approaches allowing regulated production of shRNAs based on modified RNA...

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Hlavní autoři: Pluta, Krzysztof, Diehl, William, Zhang, Xian-Yang, Kutner, Robert, Bialkowska, Agnieszka, Reiser, Jakob
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959519/
https://ncbi.nlm.nih.gov/pubmed/17634114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-7-41
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