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Comparative analysis of HIV-1-based lentiviral vectors bearing lyssavirus glycoproteins for neuronal gene transfer

BACKGROUND: The delivery of therapeutic genes to the central nervous system (CNS) using viral vectors represents an appealing strategy for the treatment of nerve injury and disorders of the CNS. Important factors determining CNS targeting include tropism of the viral vectors and retrograde transport...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Federici, Thais, Kutner, Robert, Zhang, Xian-Yang, Kuroda, Hitoshi, Tordo, Noël, Boulis, Nicholas M, Reiser, Jakob
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639530/
https://ncbi.nlm.nih.gov/pubmed/19144125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-7-1
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