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Transgenic Mice Overexpressing Peroxiredoxin 6 Show Increased Resistance to Lung Injury in Hyperoxia

Peroxiredoxin 6 (Prdx6) is a novel peroxidase enzyme that is expressed at a high level in the lung. We tested the hypothesis that transgenic (Tg) mice overexpressing Prdx6 would exhibit increased resistance to hyperoxia-induced lung injury. Wild-type and Tg mice were exposed to 100% O(2) and evaluat...

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Autors principals: Wang, Yan, Phelan, Shelley A., Manevich, Yefim, Feinstein, Sheldon I., Fisher, Aron B.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644209/
https://ncbi.nlm.nih.gov/pubmed/16399955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0333OC
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