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PTEN Loss Promotes Mitochondrially Dependent Type II Fas-Induced Apoptosis via PEA-15
Two distinct biochemical signals are delivered by the CD95/Fas death receptor. The molecular basis for the differential mitochondrially independent (type I) and mitochondrially dependent (type II) Fas apoptosis pathways is unknown. By analyzing 24 Fas-sensitive tumor lines, we now demonstrate that e...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643821/ https://ncbi.nlm.nih.gov/pubmed/19103758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01660-08 |
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