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Molecular Pathways: Intercellular PTEN and the Potential of PTEN Restoration Therapy

Phosphatase and Tensin homologue deleted on chromosome ten (PTEN) acts a tumor suppressor through both PI3K dependent and independent mechanisms. Reduced PTEN activity has been shown to affect not only tumor cell proliferation and survival but also impacts the micro-environmental context in which na...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Hopkins, Benjamin D., Parsons, Ramon E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362520/
https://ncbi.nlm.nih.gov/pubmed/25361917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2661
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