Host Responses to Wild-Type and Attenuated Herpes Simplex Virus Infection in the Absence of Stat1

Humans and mice lacking the interferon signaling molecule Stat1 are sensitive to a variety of pathogens due to their presumed inability to mount a strong innate immune response. The herpes simplex virus type 1 (HSV-1) virion host shutoff (vhs) protein is a multifunctional immunomodulator that counte...

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Hlavní autoři: Pasieka, Tracy Jo, Cilloniz, Cristian, Lu, Betty, Teal, Thomas H., Proll, Sean C., Katze, Michael G., Leib, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643728/
https://ncbi.nlm.nih.gov/pubmed/19109391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02007-08
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