The Chaperones Hsp90 and Cdc37 Mediate the Maturation and Stabilization of Protein Kinase C through a Conserved PXXP Motif in the C-terminal Tail

The life cycle of protein kinase C (PKC) is tightly controlled by mechanisms that mature the enzyme, sustain the activation-competent enzyme, and degrade the enzyme. Here we show that a conserved PXXP motif (Kannan, N., Haste, N., Taylor, S. S., and Neuwald, A. F. (2007) Proc. Natl. Acad. Sci. U. S....

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Detaylı Bibliyografya
Asıl Yazarlar: Gould, Christine M., Kannan, Natarajan, Taylor, Susan S., Newton, Alexandra C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2009
Konular:
Mechanisms of Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643500/
https://ncbi.nlm.nih.gov/pubmed/19091746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808436200
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