Synergy between Natriuretic Peptides and Phosphodiesterase 5 Inhibitors Ameliorates Pulmonary Arterial Hypertension

Rationale: Phosphodiesterase 5 (PDE5) inhibitors (e.g., sildenafil) are selective pulmonary vasodilators in patients with pulmonary arterial hypertension. The mechanism(s) underlying this specificity remains unclear, but studies in genetically modified animals suggest it might be dependent on natriu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Baliga, Reshma S., Zhao, Lan, Madhani, Melanie, Lopez-Torondel, Belen, Visintin, Cristina, Selwood, David, Wilkins, Martin R., MacAllister, Raymond J., Hobbs, Adrian J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2008
Pynciau:
H. Pulmonary Vascular Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643218/
https://ncbi.nlm.nih.gov/pubmed/18689467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200801-121OC
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