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Metal Binding Domains 3 and 4 of the Wilson Disease Protein: Solution Structure and Interaction with the Copper(I) Chaperone HAH1

The Wilson disease protein or ATP7B is a P(1B)-type ATPase involved in human copper homeostasis. The extended N-terminus of ATP7B protrudes into the cytosol and contains six Cu(I) binding domains. This report presents the NMR structure of the polypeptide consisting of soluble Cu(I) binding domains 3...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Banci, Lucia, Bertini, Ivano, Cantini, Francesca, Rosenzweig, Amy C., Yatsunyk, Liliya A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643083/
https://ncbi.nlm.nih.gov/pubmed/18558714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8004736
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