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Structural Polymorphism of 441-Residue Tau at Single Residue Resolution

Alzheimer disease is characterized by abnormal protein deposits in the brain, such as extracellular amyloid plaques and intracellular neurofibrillary tangles. The tangles are made of a protein called tau comprising 441 residues in its longest isoform. Tau belongs to the class of natively unfolded pr...

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書誌詳細
主要な著者: Mukrasch, Marco D, Bibow, Stefan, Korukottu, Jegannath, Jeganathan, Sadasivam, Biernat, Jacek, Griesinger, Christian, Mandelkow, Eckhard, Zweckstetter, Markus
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642882/
https://ncbi.nlm.nih.gov/pubmed/19226187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000034
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