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Autophagy Provides Nutrients but Can Lead to Chop-dependent Induction of Bim to Sensitize Growth Factor–deprived Cells to Apoptosis

Tissue homeostasis is controlled by the availability of growth factors, which sustain exogenous nutrient uptake and prevent apoptosis. Although autophagy can provide an alternate intracellular nutrient source to support essential basal metabolism of apoptosis-resistant growth factor–withdrawn cells,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Altman, Brian J., Wofford, Jessica A., Zhao, Yuxing, Coloff, Jonathan L., Ferguson, Emily C., Wieman, Heather L., Day, Amanda E., Ilkayeva, Olga, Rathmell, Jeffrey C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642748/
https://ncbi.nlm.nih.gov/pubmed/19109422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-08-0829
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